I quite enjoyed this (a lot more than I enjoyed Resurrection Inc.). This is really a pretty straight-forward action/adventure style story (the same sort of story as, e.g., 24). I read a few stories along these general lines (e.g. the Dan Brown books) over the second half of 2008, and they were a nice break (I read more in this genre a long time back), although nothing was mind-blowingly great.
I gathered that Fallout continues the story of characters from an earlier story (Virtual Destruction), but not having read that didn’t effect my enjoyment of this at all – as far as I can tell, the story is completely standalone.
The plot was a little predictable – it wasn’t hard to guess who the villains would turn out to be, but the mystery wasn’t really the appeal of the book, and the characters were likable enough.
Overall, well worth a read.